Stacey L. McDonald's Copper-Catalyzed Electrophilic Amination of sp2 and sp3 C−H PDF

By Stacey L. McDonald

This thesis studies the newest advancements within the direct amination of assorted C−H bonds utilizing an H−Zn exchange/electrophilic amination strategy.  McDonald and associates show this method of be a speedy and robust strategy for getting access to a number of functionalized amines.

The fabric defined during this publication indicates how McDonald accomplished C−H zincation utilizing powerful, non-nucleophilic zinc bases and next electrophilic amination of the corresponding zinc carbanions with copper as a catalyst and O-benzoylhydroxylamines because the electrophilic nitrogen resource.

McDonald’s findings are of relevance to medicinal chemistry, drug discovery and fabrics technological know-how. Her thesis is a resource of idea for scientists coming into the sector and scholars starting their PhD in a similar area. 

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Copper-Catalyzed Electrophilic Amination of sp2 and sp3 C−H Bonds (Springer Theses) by Stacey L. McDonald


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