Stefano Mangani's Disruption of Protein-Protein Interfaces: In Search of New PDF

By Stefano Mangani

"Disruption of Protein-Protein Interfaces" studies the newest advancements and destiny views in drug discovery at protein-protein interfaces. The authors element experimental and computational instruments to take on the topic and spotlight the contribution of the Italian examine group to the sector. facts indicates that blockading or modulating protein-protein interactions may well result in the advance of valuable new medicines. accordingly, lately nice attempt has been devoted to unveiling the molecular info of protein-protein interfaces through structural options e.g. X-ray diffraction, NMR spectroscopy. This booklet, written and edited by way of leaders within the box, offers examples from the literature of successes and screw ups to enhance drug-like molecules potent in interacting at protein-protein interfaces.

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Disruption of Protein-Protein Interfaces: In Search of New Inhibitors by Stefano Mangani


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